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Population Pharmacokinetics of Tofacitinib in Patients With Moderate to Severe Ulcerative Colitis

Tofacitinib is an oral, small molecule Janus kinase inhibitor for the treatment of ulcerative colitis (UC). We characterized tofacitinib pharmacokinetics in patients with moderate to severe UC, and the effects of covariates on variability in pharmacokinetic parameter estimates. Data were pooled from...

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Bibliografiske detaljer
Udgivet i:Clin Pharmacol Drug Dev
Main Authors: Vong, Camille, Martin, Steven W., Deng, Chenhui, Xie, Rujia, Ito, Kaori, Su, Chinyu, Sandborn, William J., Mukherjee, Arnab
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986169/
https://ncbi.nlm.nih.gov/pubmed/33513294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.899
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