Population Pharmacokinetics of Tofacitinib in Patients With Moderate to Severe Ulcerative Colitis

Tofacitinib is an oral, small molecule Janus kinase inhibitor for the treatment of ulcerative colitis (UC). We characterized tofacitinib pharmacokinetics in patients with moderate to severe UC, and the effects of covariates on variability in pharmacokinetic parameter estimates. Data were pooled from...

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Bibliographic Details
Published in:Clin Pharmacol Drug Dev
Main Authors: Vong, Camille, Martin, Steven W., Deng, Chenhui, Xie, Rujia, Ito, Kaori, Su, Chinyu, Sandborn, William J., Mukherjee, Arnab
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2021
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986169/
https://ncbi.nlm.nih.gov/pubmed/33513294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.899
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