Venous thromboembolic events in the tofacitinib ulcerative colitis clinical development programme

BACKGROUND: Tofacitinib is an oral, small molecule JAK inhibitor for the treatment of ulcerative colitis (UC). AIM: To report incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE) in the tofacitinib UC programme. METHODS: DVT and PE were evaluated from one phase 2 and two phase 3 induc...

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Udgivet i:Aliment Pharmacol Ther
Main Authors: Sandborn, William J., Panés, Julian, Sands, Bruce E., Reinisch, Walter, Su, Chinyu, Lawendy, Nervin, Koram, Nana, Fan, Haiyun, Jones, Thomas V., Modesto, Irene, Quirk, Daniel, Danese, Silvio
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Tofacitinib and Venous Thromboembolism in Uc
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899755/
https://ncbi.nlm.nih.gov/pubmed/31599001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.15514
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