Assessment of DNA damage with an adapted independent reaction time approach implemented in Geant4‐DNA for the simulation of diffusion‐controlled reactions between radio‐induced reactive species and a chromatin fiber

PURPOSE: Simulation of indirect damage originating from the attack of free radical species produced by ionizing radiation on biological molecules based on the independent pair approximation is investigated in this work. In addition, a new approach, relying on the independent pair approximation that...

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Detalhes bibliográficos
Publicado no:Med Phys
Main Authors: Tran, Hoang Ngoc, Ramos‐Méndez, José, Shin, Wook‐Geun, Perrot, Yann, Faddegon, Bruce, Okada, Shogo, Karamitros, Mathieu, Davídková, Marie, Štěpán, Václav, Incerti, Sébastien, Villagrasa, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
BIOLOGICAL PHYSICS AND RESPONSE PREDICTION
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986154/
https://ncbi.nlm.nih.gov/pubmed/33232522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mp.14612
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