Assessment of DNA damage with an adapted independent reaction time approach implemented in Geant4‐DNA for the simulation of diffusion‐controlled reactions between radio‐induced reactive species and a chromatin fiber

PURPOSE: Simulation of indirect damage originating from the attack of free radical species produced by ionizing radiation on biological molecules based on the independent pair approximation is investigated in this work. In addition, a new approach, relying on the independent pair approximation that...

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Bibliografske podrobnosti
izdano v:Med Phys
Main Authors: Tran, Hoang Ngoc, Ramos‐Méndez, José, Shin, Wook‐Geun, Perrot, Yann, Faddegon, Bruce, Okada, Shogo, Karamitros, Mathieu, Davídková, Marie, Štěpán, Václav, Incerti, Sébastien, Villagrasa, Carmen
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
BIOLOGICAL PHYSICS AND RESPONSE PREDICTION
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986154/
https://ncbi.nlm.nih.gov/pubmed/33232522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mp.14612
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