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Light‐Activated Electron Transfer and Catalytic Mechanism of Carnitine Oxidation by Rieske‐Type Oxygenase from Human Microbiota

Oxidation of quaternary ammonium substrate, carnitine by non‐heme iron containing Acinetobacter baumannii (Ab) oxygenase CntA/reductase CntB is implicated in the onset of human cardiovascular disease. Herein, we develop a blue‐light (365 nm) activation of NADH coupled to electron paramagnetic resona...

詳細記述

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: Shanmugam, Muralidharan, Quareshy, Mussa, Cameron, Alexander D., Bugg, Timothy D. H., Chen, Yin
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986066/
https://ncbi.nlm.nih.gov/pubmed/33180358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202012381
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