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Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota
Dietary intake of l-carnitine can promote cardiovascular diseases in humans through microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine N-oxide by hepatic flavin-containing monooxygenases. Although our microbiota are responsible for TMA formation from carnitin...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3964110/ https://ncbi.nlm.nih.gov/pubmed/24591617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316569111 |
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