Retuning Rieske-type Oxygenases to Expand Substrate Range

Rieske-type oxygenases are promising biocatalysts for the destruction of persistent pollutants or for the synthesis of fine chemicals. In this work, we explored pathways through which Rieske-type oxygenases evolve to expand their substrate range. BphAE(p4), a variant biphenyl dioxygenase generated f...

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Bibliografiske detaljer
Main Authors: Mohammadi, Mahmood, Viger, Jean-François, Kumar, Pravindra, Barriault, Diane, Bolin, Jeffrey T., Sylvestre, Michel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149352/
https://ncbi.nlm.nih.gov/pubmed/21653696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255174
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