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A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes
The transcription factor vitamin D receptor (VDR) is the high affinity nuclear target of the biologically active form of vitamin D(3) (1,25(OH)(2)D(3)). In order to identify pure genomic transcriptional effects of 1,25(OH)(2)D(3), we used VDR cistrome, transcriptome and open chromatin data, obtained...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7985518/ https://ncbi.nlm.nih.gov/pubmed/33753848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86032-5 |
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