Mitochondrial DNA deletion mutations increase exponentially with age in human skeletal muscle

BACKGROUND: Mitochondrial DNA (mtDNA) deletion mutations lead to electron transport chain deficient cells and age-induced cell loss in multiple tissues and mammalian species. Accurate quantitation of somatic mtDNA deletion mutations could serve as an index of age-induced cell loss. Quantitation of m...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Aging Clin Exp Res
Auteurs principaux: Herbst, Allen, Lee, Cathy C., Vandiver, Amy R., Aiken, Judd M., McKenzie, Debbie, Hoang, Austin, Allison, David, Liu, Nianjun, Wanagat, Jonathan
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985047/
https://ncbi.nlm.nih.gov/pubmed/32965609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40520-020-01698-7
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires