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Mitochondrial DNA deletion mutations increase exponentially with age in human skeletal muscle
BACKGROUND: Mitochondrial DNA (mtDNA) deletion mutations lead to electron transport chain deficient cells and age-induced cell loss in multiple tissues and mammalian species. Accurate quantitation of somatic mtDNA deletion mutations could serve as an index of age-induced cell loss. Quantitation of m...
Shranjeno v:
| izdano v: | Aging Clin Exp Res |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7985047/ https://ncbi.nlm.nih.gov/pubmed/32965609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40520-020-01698-7 |
| Oznake: |
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