Morphine coordinates SST and PV interneurons in the prelimbic cortex to disinhibit pyramidal neurons and enhance reward

Opioids, such as morphine, are clinic analgesics which induce euphoria. Morphine exposure modifies the excitability and functional interactions between neurons, while the underlying cellular and molecular mechanisms, especially how morphine assembles heterogeneous interneurons (INs) in prelimbic cor...

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Bibliografiske detaljer
Udgivet i:Mol Psychiatry
Main Authors: Jiang, Changyou, Wang, Xueying, Le, Qiumin, Liu, Peipei, Liu, Cao, Wang, Zhilin, He, Guanhong, Zheng, Ping, Wang, Feifei, Ma, Lan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985023/
https://ncbi.nlm.nih.gov/pubmed/31413370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0480-7
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