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Morphine coordinates SST and PV interneurons in the prelimbic cortex to disinhibit pyramidal neurons and enhance reward

Opioids, such as morphine, are clinic analgesics which induce euphoria. Morphine exposure modifies the excitability and functional interactions between neurons, while the underlying cellular and molecular mechanisms, especially how morphine assembles heterogeneous interneurons (INs) in prelimbic cor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Psychiatry
Egile Nagusiak: Jiang, Changyou, Wang, Xueying, Le, Qiumin, Liu, Peipei, Liu, Cao, Wang, Zhilin, He, Guanhong, Zheng, Ping, Wang, Feifei, Ma, Lan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985023/
https://ncbi.nlm.nih.gov/pubmed/31413370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0480-7
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