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The Developmental Switch in Bacteriophage λ: A Critical Role of the Cro Protein

Bacteriophage λ of Escherichia coli has two alternative life cycles after infection–host survival with lysogen formation, or host lysis and phage production. In a lysogen, CI represses the two lytic promoters, pR and pL, and activates its own transcription from the auto-regulated pRM promoter. Durin...

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Bibliographic Details
Published in:J Mol Biol
Main Authors: Lee, Sangmi, Lewis, Dale E.A., Adhya, Sankar
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984726/
https://ncbi.nlm.nih.gov/pubmed/29158090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.11.005
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