Hyperpolarized [1-(13)C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

PURPOSE: To evaluate the potential of hyperpolarized [1-(13)C]-pyruvate magnetic resonance spectroscopic imaging (MRSI) of prostate cancer as a predictive biomarker for targeting the Warburg effect. EXPERIMENTAL DESIGN: Two human prostate cancer cell lines (DU145 and PC3) were grown as xenografts. T...

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Publicat a:Clin Cancer Res
Autors principals: Scroggins, Bradley T., Matsuo, Masayuki, White, Ayla O., Saito, Keita, Munasinghe, Jeeva P., Sourbier, Carole, Yamamoto, Kazutoshi, Diaz, Vivian, Takakusagi, Yoichi, Ichikawa, Kazuhiro, Mitchell, James B., Krishna, Murali C., Citrin, Deborah E.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984723/
https://ncbi.nlm.nih.gov/pubmed/29599412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1957
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