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SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense

The skin innate immune response to methicillin-resistant Staphylococcus aureus (MRSA) culminates in the formation of an abscess to prevent bacterial spread and tissue damage. Pathogen recognition receptors (PRRs) dictate the balance between microbial control and injury. Therefore, intracellular brak...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Klopfenstein, Nathan, Brandt, Stephanie L., Castellanos, Sydney, Gunzer, Matthias, Blackman, Amondrea, Serezani, C. Henrique
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984627/
https://ncbi.nlm.nih.gov/pubmed/33690673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009387
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