SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense

The skin innate immune response to methicillin-resistant Staphylococcus aureus (MRSA) culminates in the formation of an abscess to prevent bacterial spread and tissue damage. Pathogen recognition receptors (PRRs) dictate the balance between microbial control and injury. Therefore, intracellular brak...

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Udgivet i:PLoS Pathog
Main Authors: Klopfenstein, Nathan, Brandt, Stephanie L., Castellanos, Sydney, Gunzer, Matthias, Blackman, Amondrea, Serezani, C. Henrique
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984627/
https://ncbi.nlm.nih.gov/pubmed/33690673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009387
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