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SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense

The skin innate immune response to methicillin-resistant Staphylococcus aureus (MRSA) culminates in the formation of an abscess to prevent bacterial spread and tissue damage. Pathogen recognition receptors (PRRs) dictate the balance between microbial control and injury. Therefore, intracellular brak...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Klopfenstein, Nathan, Brandt, Stephanie L., Castellanos, Sydney, Gunzer, Matthias, Blackman, Amondrea, Serezani, C. Henrique
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984627/
https://ncbi.nlm.nih.gov/pubmed/33690673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009387
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