Optical mapping of cAMP signaling at the nanometer scale

Cells relay a plethora of extracellular signals to specific cellular responses using only a few second messengers, such as cAMP. To explain signaling specificity, cAMP-degrading phosphodiesterases (PDEs) have been suggested to confine cAMP to distinct cellular compartments. However, measured rates o...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Bock, Andreas, Annibale, Paolo, Konrad, Charlotte, Hannawacker, Annette, Anton, Selma E., Maiellaro, Isabella, Zabel, Ulrike, Sivaramakrishnan, Sivaraj, Falcke, Martin, Lohse, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984459/
https://ncbi.nlm.nih.gov/pubmed/32846156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.07.035
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