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Pharmacokinetic variability of factor VIII concentrates in Chinese pediatric patients with moderate or severe hemophilia A

IMPORTANCE: The use of factor VIII (FVIII) concentrates under pharmacokinetic (PK) guidance has become the main approach for treatment of hemophilia. However, limited PK research has been conducted in Chinese pediatric patients. OBJECTIVE: To investigate the PK parameters of various FVIII concentrat...

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Bibliografiske detaljer
Udgivet i:Pediatr Investig
Main Authors: Chen, Zhenping, Huang, Kun, Li, Gang, Zhen, Yingzi, Wu, Xinyi, Di, Ai, Liu, Guoqing, Li, Zekun, Alfonso, Iorio, Wu, Runhui
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983998/
https://ncbi.nlm.nih.gov/pubmed/33778426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ped4.12252
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