Pharmacokinetic variability of factor VIII concentrates in Chinese pediatric patients with moderate or severe hemophilia A

IMPORTANCE: The use of factor VIII (FVIII) concentrates under pharmacokinetic (PK) guidance has become the main approach for treatment of hemophilia. However, limited PK research has been conducted in Chinese pediatric patients. OBJECTIVE: To investigate the PK parameters of various FVIII concentrat...

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Vydáno v:Pediatr Investig
Hlavní autoři: Chen, Zhenping, Huang, Kun, Li, Gang, Zhen, Yingzi, Wu, Xinyi, Di, Ai, Liu, Guoqing, Li, Zekun, Alfonso, Iorio, Wu, Runhui
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983998/
https://ncbi.nlm.nih.gov/pubmed/33778426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ped4.12252
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