IFITM3‐specific antibody reveals IFN preferences and slow IFN induction of the antiviral factor IFITM3 in humans

Using a specific antibody, we found that expression of the viral restriction factor IFITM3 differs across cell types within the immune compartment with higher expression in myeloid rather than lymphoid cells. IFITM3 expression was increased following IFN stimulation, mostly type I, in immune cells,...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Wellington, Dannielle, Yin, Zixi, Abdel‐Haq, Adi, Zhang, Liwei, Forbester, Jessica, Kite, Kerry, Rajapaksa, Ushani, Laurenson‐Schafer, Henry, Makvandi‐Nejad, Shokouh, Jin, Boquan, Bowes, Emma, Manoharan, Krishnageetha, Maldonado‐Perez, David, Verrill, Clare, Humphreys, Ian R., Dong, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Letters to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983929/
https://ncbi.nlm.nih.gov/pubmed/33125710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048706
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