IFITM3‐specific antibody reveals IFN preferences and slow IFN induction of the antiviral factor IFITM3 in humans

Using a specific antibody, we found that expression of the viral restriction factor IFITM3 differs across cell types within the immune compartment with higher expression in myeloid rather than lymphoid cells. IFITM3 expression was increased following IFN stimulation, mostly type I, in immune cells,...

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Veröffentlicht in:Eur J Immunol
Hauptverfasser: Wellington, Dannielle, Yin, Zixi, Abdel‐Haq, Adi, Zhang, Liwei, Forbester, Jessica, Kite, Kerry, Rajapaksa, Ushani, Laurenson‐Schafer, Henry, Makvandi‐Nejad, Shokouh, Jin, Boquan, Bowes, Emma, Manoharan, Krishnageetha, Maldonado‐Perez, David, Verrill, Clare, Humphreys, Ian R., Dong, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Letters to the Editor
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983929/
https://ncbi.nlm.nih.gov/pubmed/33125710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048706
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