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Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease

The etiology of the common, sporadic form of Alzheimer's disease (sAD) is unknown. We hypothesize that tau pathology within select projection neurons with susceptible microenvironments can initiate sAD. This postulate rests on extensive data demonstrating that in human brains tau pathology appe...

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Bibliografski detalji
Izdano u:Alzheimers Dement
Glavni autori: Arnsten, Amy F. T., Datta, Dibyadeep, Tredici, Kelly Del, Braak, Heiko
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983919/
https://ncbi.nlm.nih.gov/pubmed/33075193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12192
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