Detection of Microsatellite Instability via Circulating Tumor DNA and Response to Immunotherapy in Metastatic Castration-Resistant Prostate Cancer: A Case Series

Pembrolizumab has been approved by the US Food and Drug Administration for the treatment of metastatic or unresectable solid tumors that are microsatellite instability-high (MSI-H) or mismatch repair deficient. Blood-based circulating tumor DNA (ctDNA) assays have been validated to identify tumors w...

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Udgivet i:Case Rep Oncol
Main Authors: Ravindranathan, Deepak, Russler, Greta Anne, Yantorni, Lauren, Drusbosky, Leylah M., Bilen, Mehmet Asim
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2021
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983538/
https://ncbi.nlm.nih.gov/pubmed/33776702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000512819
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