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Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts
Detailed phylogenies of tumor populations can recount the history and chronology of critical events during cancer progression, such as metastatic dissemination. We applied a Cas9-based, single-cell lineage tracer to study the rates, routes, and drivers of metastasis in a lung cancer xenograft mouse...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7983364/ https://ncbi.nlm.nih.gov/pubmed/33479121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc1944 |
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