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Inference of single-cell phylogenies from lineage tracing data using Cassiopeia
The pairing of CRISPR/Cas9-based gene editing with massively parallel single-cell readouts now enables large-scale lineage tracing. However, the rapid growth in complexity of data from these assays has outpaced our ability to accurately infer phylogenetic relationships. First, we introduce Cassiopei...
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| Veröffentlicht in: | Genome Biol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7155257/ https://ncbi.nlm.nih.gov/pubmed/32290857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02000-8 |
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