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Biologically Enhanced Genome-Wide Association Study Provides Further Evidence for Candidate Loci and Discovers Novel Loci That Influence Risk of Anterior Cruciate Ligament Rupture in a Dog Model

Anterior cruciate ligament (ACL) rupture is a common condition that disproportionately affects young people, 50% of whom will develop knee osteoarthritis (OA) within 10 years of rupture. ACL rupture exhibits both hereditary and environmental risk factors, but the genetic basis of the disease remains...

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Pubblicato in:Front Genet
Autori principali: Baker, Lauren A., Momen, Mehdi, McNally, Rachel, Berres, Mark E., Binversie, Emily E., Sample, Susannah J., Muir, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7982834/
https://ncbi.nlm.nih.gov/pubmed/33763109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.593515
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