Accuracy of genome-enabled polygenic risk score prediction of cruciate ligament rupture risk in the Labrador Retriever

IntroductionCanine cruciate ligament rupture (CR) is a common, complex, polygenic, orthopaedic disease in dogs that results in serious financial burden and patient morbidity even in the face of surgical correction. The goal of this study was to evaluate the clinical utility of CR polygenic risk scor...

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Hlavní autoři: Benjamin Miranda, Mehdi Momen, Susannah J. Sample, Peter Muir
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-08-01
Edice:Frontiers in Veterinary Science
Témata:
cruciate ligament rupture
dog
genome-wide association study
genomic prediction
polygenic risk score prediction
Labrador Retriever
On-line přístup:https://www.frontiersin.org/articles/10.3389/fvets.2025.1625953/full
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