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Protocol for in vitro skin fibrosis model to screen the biological effects of antifibrotic compounds

Controversies remain over the standard procedures for the modeling of skin fibrosis and its use in in vitro testing of different drugs. Here, we report a reproducible protocol for producing a skin fibrosis model using human dermal fibroblasts seeded in collagen hydrogel. Detailed procedures for the...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Alsharabasy, Amir M., Pandit, Abhay
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7982747/
https://ncbi.nlm.nih.gov/pubmed/33778781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100387
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