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Collagen triple helix repeat containing-1 exerts antifibrotic effects on human skin fibroblast and bleomycin-induced dermal fibrosis models

BACKGROUND: Systemic scleroderma (SSc) is an acquired disorder characterized by excessive deposition of extracellular matrix in the skin and internal organs. So far, the molecular mechanisms underpinning the pathogenesis of SSc have remained unknown. Collagen triple helix repeat containing-1 (CTHRC1...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Shen, Zhu, Su, Tangfeng, Chen, Jin, Xie, Zhen, Li, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246160/
https://ncbi.nlm.nih.gov/pubmed/34268414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-21-1884
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