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Preparation and Release Profiles in Vitro/Vivo of Galantamine Pamoate Loaded Poly (Lactideco-Glycolide) (PLGA) Microspheres

Patient’s poor compliance and the high risk of toxic effects limit the clinical use of galantamine hydrobromide. To overcome these drawbacks, the sustained-release galantamine pamoate microspheres (GLT-PM-MS) were successfully developed using an oil/water emulsion solvent evaporation method in this...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Du, Liping, Liu, Shankui, Hao, Guizhou, Zhang, Li, Zhou, Miaomiao, Bao, Yueqing, Ding, Bing, Sun, Qinyong, Zhang, Guimin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7982595/
https://ncbi.nlm.nih.gov/pubmed/33762929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.619327
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