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Preparation of poly(lactide-co-glycolide) microspheres and evaluation of pharmacokinetics and tissue distribution of BDMC-PLGA-MS in rats

The aim of the present study was to develop a novel long-acting Poly (lactic-co-glycolic acid) (PLGA)-based microspheres formulation of Bisdemethoxycurcum (BDMC) by emulsion-solvent evaporation method. Meanwhile, the effects of the volume ratio of the dispersed phase and continuous phase, the concen...

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Опубликовано в: :Asian J Pharm Sci
Главные авторы: Li, Guozhuan, Yao, Liang, Li, Jing, Qin, Xiaoyan, Qiu, Zhen, Chen, Weidong
Формат: Artigo
Язык:Inglês
Опубликовано: Shenyang Pharmaceutical University 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032131/
https://ncbi.nlm.nih.gov/pubmed/32104381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2017.09.002
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