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PCNA-associated factor (KIAA0101/PCLAF) overexpression and gene copy number alterations in hepatocellular carcinoma tissues

BACKGROUND: PCNA-associated factor, the protein encoded by the KIAA0101/PCLAF gene, is a cell-cycle regulated oncoprotein that regulates DNA synthesis, maintenance of DNA methylation, and DNA-damage bypass, through the interaction with the human sliding clamp PCNA. KIAA0101/PCLAF is overexpressed in...

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Vydáno v:BMC Cancer
Hlavní autoři: Tantiwetrueangdet, Anchalee, Panvichian, Ravat, Sornmayura, Pattana, Leelaudomlipi, Surasak, Macoska, Jill A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981960/
https://ncbi.nlm.nih.gov/pubmed/33743635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-07994-3
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