Missense Mutations in Exons 18–24 of EGFR in Hepatocellular Carcinoma Tissues

Epidermal growth factor receptor (EGFR), a transmembrane tyrosine kinase receptor, plays important roles in various cancers. In nonsmall cell lung cancer (NSCLC), EGFR mutations cluster around the ATP-binding pocket (exons 18–21) and some of these mutations activate the kinase and induce an increase...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Panvichian, Ravat, Tantiwetrueangdet, Anchalee, Sornmayura, Pattana, Leelaudomlipi, Surasak
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575985/
https://ncbi.nlm.nih.gov/pubmed/26436086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/171845
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