A cookbook for DNase Hi-C

BACKGROUND: The Hi-C technique is widely employed to study the 3-dimensional chromatin architecture and to assemble genomes. The conventional in situ Hi-C protocol employs restriction enzymes to digest chromatin, which results in nonuniform genomic coverage. Using sequence-agnostic restriction enzym...

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Bibliografiske detaljer
Udgivet i:Epigenetics Chromatin
Main Authors: Gridina, Maria, Mozheiko, Evgeniy, Valeev, Emil, Nazarenko, Ludmila P., Lopatkina, Maria E., Markova, Zhanna G., Yablonskaya, Maria I., Voinova, Viktoria Yu, Shilova, Nadezhda V., Lebedev, Igor N., Fishman, Veniamin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Methodology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981840/
https://ncbi.nlm.nih.gov/pubmed/33743768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-021-00389-5
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