NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

This is the first report of a NACC2‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome profilin...

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Detalhes bibliográficos
Publicado no:Clin Case Rep
Main Authors: Britton, Heidi M., Levine, Adrian B., Shen, Yaoqing, Mungall, Karen, Serrano, Jonathan, Snuderl, Matija, Pleasance, Erin, Jones, Steven J. M., Laskin, Janessa, Marra, Marco A., Rassekh, Shahrad R., Deyell, Rebecca, Yip, Stephen, Cheng, Sylvia, Dunham, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Case Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981675/
https://ncbi.nlm.nih.gov/pubmed/33768871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.3804
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