NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

This is the first report of a NACC2‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome profilin...

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Bibliografske podrobnosti
izdano v:Clin Case Rep
Main Authors: Britton, Heidi M., Levine, Adrian B., Shen, Yaoqing, Mungall, Karen, Serrano, Jonathan, Snuderl, Matija, Pleasance, Erin, Jones, Steven J. M., Laskin, Janessa, Marra, Marco A., Rassekh, Shahrad R., Deyell, Rebecca, Yip, Stephen, Cheng, Sylvia, Dunham, Chris
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Case Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981675/
https://ncbi.nlm.nih.gov/pubmed/33768871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.3804
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