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Tying the knot in the tetrahydrofolate (THF) riboswitch: a molecular basis for gene regulation
Effective gene regulation by the tetrahydrofolate riboswitch depends not only on ligand affinity but also on the kinetics of ligand association, which involves two cooperative binding sites. We have determined a 1.9-Å resolution crystal structure of the ligand-free THF riboswitch aptamer. The pseudo...
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| Published in: | J Struct Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7981257/ https://ncbi.nlm.nih.gov/pubmed/33571639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2021.107703 |
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