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Tying the knot in the tetrahydrofolate (THF) riboswitch: a molecular basis for gene regulation

Effective gene regulation by the tetrahydrofolate riboswitch depends not only on ligand affinity but also on the kinetics of ligand association, which involves two cooperative binding sites. We have determined a 1.9-Å resolution crystal structure of the ligand-free THF riboswitch aptamer. The pseudo...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Struct Biol
Egile Nagusiak: Wilt, Haley M., Yu, Ping, Tan, Kemin, Wang, Yun-Xing, Stagno, Jason R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981257/
https://ncbi.nlm.nih.gov/pubmed/33571639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2021.107703
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