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Opioid therapy vs. multimodal analgesia in head and neck Cancer (OPTIMAL-HN): study protocol for a randomized clinical trial

BACKGROUND: Radiation-induced mucositis (RIM) pain confers substantial morbidity for head and neck cancer (HNC) patients undergoing radiotherapy alone (RT) or chemoradiotherapy (CRT), often reducing treatment compliance. However, no standard currently exists for the treatment of RIM, and high dose o...

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Publicado en:BMC Palliat Care
Autores principales: Zayed, Sondos, Lang, Pencilla, Mendez, Lucas C., Read, Nancy, Sathya, Jinka, Venkatesan, Varagur, Moulin, Dwight E., Warner, Andrew, Palma, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980584/
https://ncbi.nlm.nih.gov/pubmed/33740977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12904-021-00735-0
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