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Opioid therapy vs. multimodal analgesia in head and neck Cancer (OPTIMAL-HN): study protocol for a randomized clinical trial

BACKGROUND: Radiation-induced mucositis (RIM) pain confers substantial morbidity for head and neck cancer (HNC) patients undergoing radiotherapy alone (RT) or chemoradiotherapy (CRT), often reducing treatment compliance. However, no standard currently exists for the treatment of RIM, and high dose o...

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Detalhes bibliográficos
Publicado no:BMC Palliat Care
Main Authors: Zayed, Sondos, Lang, Pencilla, Mendez, Lucas C., Read, Nancy, Sathya, Jinka, Venkatesan, Varagur, Moulin, Dwight E., Warner, Andrew, Palma, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980584/
https://ncbi.nlm.nih.gov/pubmed/33740977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12904-021-00735-0
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