Opioid therapy vs. multimodal analgesia in head and neck Cancer (OPTIMAL-HN): study protocol for a randomized clinical trial

BACKGROUND: Radiation-induced mucositis (RIM) pain confers substantial morbidity for head and neck cancer (HNC) patients undergoing radiotherapy alone (RT) or chemoradiotherapy (CRT), often reducing treatment compliance. However, no standard currently exists for the treatment of RIM, and high dose o...

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Veröffentlicht in:BMC Palliat Care
Hauptverfasser: Zayed, Sondos, Lang, Pencilla, Mendez, Lucas C., Read, Nancy, Sathya, Jinka, Venkatesan, Varagur, Moulin, Dwight E., Warner, Andrew, Palma, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Study Protocol
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980584/
https://ncbi.nlm.nih.gov/pubmed/33740977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12904-021-00735-0
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