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Propofol impairs specification of retinal cell types in zebrafish by inhibiting Zisp-mediated Noggin-1 palmitoylation and trafficking

BACKGROUND: Propofol can have adverse effects on developing neurons, leading to cognitive disorders, but the mechanism of such an effect remains elusive. Here, we aimed to investigate the effect of propofol on neuronal development in zebrafish and to identify the molecular mechanism(s) involved in t...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Fan, Xiaoqing, Yang, Haoran, Hu, Lizhu, Wang, Delong, Wang, Ruiting, Hao, Aijun, Chen, Xueran
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980560/
https://ncbi.nlm.nih.gov/pubmed/33743805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02204-0
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