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Oligomeric assembly regulating mitochondrial HtrA2 function as examined by methyl-TROSY NMR
Human High temperature requirement A2 (HtrA2) is a mitochondrial protease chaperone that plays an important role in cellular proteostasis and in regulating cell-signaling events, with aberrant HtrA2 function leading to neurodegeneration and parkinsonian phenotypes. Structural studies of the enzyme h...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7980377/ https://ncbi.nlm.nih.gov/pubmed/33692127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025022118 |
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