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Fluorescence Assessment of the AmpR-Signaling Network of Pseudomonas aeruginosa to Exposure to β‑Lactam Antibiotics

Gram-negative bacteria have evolved an elaborate pathway to sense and respond to exposure to β-lactam antibiotics. The β-lactam antibiotics inhibit penicillin-binding proteins, whereby the loss of their activities alters/damages the cell-wall peptidoglycan. Bacteria sense this damage and remove the...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Dik, David A., Kim, Choon, Madukoma, Chinedu S., Fisher, Jed F., Shrout, Joshua D., Mobashery, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980316/
https://ncbi.nlm.nih.gov/pubmed/31990176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00875
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