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Muropeptide Binding and the X-Ray Structure of the Effector Domain of the Transcriptional Regulator AmpR of Pseudomonas aeruginosa

A complex link between cell-wall recycling/repair and the manifestation of resistance to β-lactam antibiotics in many Enterobacteriaceae and Pseudomonas aeruginosa exists. This process is mediated by specific cell-wall-derived muropeptide products. These muropeptides are internalized into the cytopl...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Dik, David A., Domínguez-Gil, Teresa, Lee, Mijoon, Hesek, Dusan, Byun, Byungjin, Fishovitz, Jennifer, Boggess, Bill, Hellman, Lance M., Fisher, Jed F., Hermoso, Juan A., Mobashery, Shahriar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436579/
https://ncbi.nlm.nih.gov/pubmed/28079369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b12819
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