Germline genetic factors influence the outcome of interferon-α therapy in polycythemia vera

Interferon-α (IFN-α)–based treatments can induce hematologic and molecular responses (HRs and MRs, respectively) in polycythemia vera (PV); however, patients do not respond equally. Germline genetic factors have been implicated in differential drug responses. We addressed the effect of common germli...

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Udgivet i:Blood
Main Authors: Jäger, Roland, Gisslinger, Heinz, Fuchs, Elisabeth, Bogner, Edith, Milosevic Feenstra, Jelena D., Weinzierl, Jakob, Schischlik, Fiorella, Gisslinger, Bettina, Schalling, Martin, Zörer, Michael, Krejcy, Kurt, Klade, Christoph, Kralovics, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2021
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980276/
https://ncbi.nlm.nih.gov/pubmed/32814349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005792
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