Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms

Ph-negative myeloproliferative neoplasms (MPNs) are hematological cancers that can be subdivided into entities with distinct clinical features. Somatic mutations in JAK2, CALR, and MPL have been described as drivers of the disease, together with a variable landscape of nondriver mutations. Despite d...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Schischlik, Fiorella, Jäger, Roland, Rosebrock, Felix, Hug, Eva, Schuster, Michael, Holly, Raimund, Fuchs, Elisabeth, Milosevic Feenstra, Jelena D., Bogner, Edith, Gisslinger, Bettina, Schalling, Martin, Rumi, Elisa, Pietra, Daniela, Fischer, Gottfried, Faé, Ingrid, Vulliard, Loan, Menche, Jörg, Haferlach, Torsten, Meggendorfer, Manja, Stengel, Anna, Bock, Christoph, Cazzola, Mario, Gisslinger, Heinz, Kralovics, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624966/
https://ncbi.nlm.nih.gov/pubmed/31064751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000519
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