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A tamoxifen receptor within a voltage-gated sodium channel

Voltage-gated sodium channels are targets for many analgesic and antiepileptic drugs whose therapeutic mechanisms and binding sites have been well characterized. We describe the identification of a previously unidentified receptor site within the NavMs voltage-gated sodium channel. Tamoxifen, an est...

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Vydáno v:Mol Cell
Hlavní autoři: Sula, Altin, Hollingworth, David, Ng, Leo C.T., Larmore, Megan, DeCaen, Paul G., Wallace, B.A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980221/
https://ncbi.nlm.nih.gov/pubmed/33503406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.12.048
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