Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness

PURPOSE: Complete congenital stationary night blindness (cCSNB) is an incurable inherited retinal disorder characterized by an ON-bipolar cell (ON-BC) defect. GRM6 mutations are the third most prevalent cause of cCSNB. The Grm6(−)(/)(−) mouse model mimics the human phenotype, showing no b-wave in th...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Varin, Juliette, Bouzidi, Nassima, Dias, Miguel Miranda De Sousa, Pugliese, Thomas, Michiels, Christelle, Robert, Camille, Desrosiers, Melissa, Sahel, José-Alain, Audo, Isabelle, Dalkara, Deniz, Zeitz, Christina
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2021
Témata:
Visual Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980044/
https://ncbi.nlm.nih.gov/pubmed/33729473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.3.24
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky