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Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness
PURPOSE: Complete congenital stationary night blindness (cCSNB) is an incurable inherited retinal disorder characterized by an ON-bipolar cell (ON-BC) defect. GRM6 mutations are the third most prevalent cause of cCSNB. The Grm6(−)(/)(−) mouse model mimics the human phenotype, showing no b-wave in th...
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| Pubblicato in: | Invest Ophthalmol Vis Sci |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Association for Research in Vision and Ophthalmology
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7980044/ https://ncbi.nlm.nih.gov/pubmed/33729473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.3.24 |
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