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Peripheral decarboxylase inhibitors paradoxically induce aromatic L-amino acid decarboxylase
Peripheral decarboxylase inhibitors (PDIs) prevent conversion of levodopa to dopamine in the blood by the enzyme aromatic L-amino acid decarboxylase (AADC). Alterations in enzyme activity may contribute to the required higher dosages of levodopa observed in many patients with Parkinson’s disease. We...
Guardat en:
| Publicat a: | NPJ Parkinsons Dis |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7979935/ https://ncbi.nlm.nih.gov/pubmed/33741988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-021-00172-z |
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