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Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation

Accurate chromosome segregation relies on the specific centromeric nucleosome–kinetochore interface. In budding yeast, the centromere CBF3 complex guides the deposition of CENP-A, an H3 variant, to form the centromeric nucleosome in a DNA sequence-dependent manner. Here, we determine the structures...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Guan, Ruifang, Lian, Tengfei, Zhou, Bing-Rui, He, Emily, Wu, Carl, Singleton, Martin, Bai, Yawen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979930/
https://ncbi.nlm.nih.gov/pubmed/33741944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21985-9
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