Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner

Hydrogen sulfide (H(2)S) is a cytoprotective redox-active metabolite that signals through protein persulfidation (R-SS(n)H). Despite the known importance of persulfidation, tissue-specific persulfidome profiles and their associated functions are not well characterized, specifically under conditions...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Bithi, Nazmin, Link, Christopher, Henderson, Yoko O., Kim, Suzie, Yang, Jie, Li, Ling, Wang, Rui, Willard, Belinda, Hine, Christopher
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979915/
https://ncbi.nlm.nih.gov/pubmed/33741971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22001-w
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